Detail Information
P450 Protein:
| P450 Symbol | CYP85A1 |
| Protein Name | Cytochrome P450 85A1 |
| Uniprot ID | Q9FMA5 |
| EC Number | 1.14.14.179 |
| Gene ID | 833889 |
| Species | Arabidopsis thaliana (Mouse-ear cress) |
| Txid | 3702 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C27H48O4 → C27H46O5 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP85A1
Substrate Information:
| Substrate Name | 6-Deoxo-28-Norcastasterone |
| Substrate Chemical Formula | C27H48O4 |
| Substrate PubChem CID | 101682290 |
| Substrate Smiles | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@H]([C@H](C4)O)O)C)C)[C@H]([C@@H](CC(C)C)O)O |
| Substrate Structure |
Product Information:
| Product Name | 28-Norcastasterone |
| Product Chemical Formula | C27H46O5 |
| Product PubChem CID | 13982110 |
| Product Smiles | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=O)[C@@H]4[C@@]3(C[C@H]([C@H](C4)O)O)C)C)[C@H]([C@@H](CC(C)C)O)O |
| Product Structure |
References:
| Title: | Brassinosteroid-6-oxidases from Arabidopsis and tomato catalyze multiple C-6 oxidations in brassinosteroid biosynthesis. |
| PMID: | 11402205 |
| Journal: | Plant physiology |
| Year: | 2001/6/1 |
| Title: | Arabidopsis CYP85A2, a cytochrome P450, mediates the Baeyer-Villiger oxidation of castasterone to brassinolide in brassinosteroid biosynthesis. |
| PMID: | 16024588 |
| Journal: | The Plant cell |
| Year: | 2005/8/1 |