Detail Information
P450 Protein:
| P450 Symbol | CYP170A1 |
| Protein Name | Bifunctional albaflavenone monooxygenase/terpene synthase |
| Uniprot ID | Q9K498 |
| EC Number | 1.14.15.39; 4.2.3.47 |
| Gene ID | 1100664 |
| Species | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| Txid | 100226 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C15H28O7P2 → C15H24 + HO7P2-3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
| RheaID | 27425 |
CYP170A1
+
Substrate Information:
| Substrate Name | (2E,6E)-Farnesyl Diphosphate |
| Substrate Chemical Formula | C15H28O7P2 |
| Substrate PubChem CID | 445713 |
| Substrate Smiles | CC(=CCC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)C |
| Substrate Structure |
Product Information:
| Product Name | (E)-Beta-Farnesene |
| Product Chemical Formula | C15H24 |
| Product PubChem CID | 5281517 |
| Product Smiles | CC(=CCCC(=CCCC(=C)C=C)C)C |
| Product Structure |
| Product Name | Diphosphate |
| Product Chemical Formula | HO7P2-3 |
| Product PubChem CID | 4097574 |
| Product Smiles | OP(=O)([O-])OP(=O)([O-])[O-] |
| Product Structure |
References:
| Title: | Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2). |
| PMID: | 18234666 |
| Journal: | The Journal of biological chemistry |
| Year: | 2008/3/28 |