Detail Information
P450 Protein:
| P450 Symbol | CYP51G1 |
| Protein Name | Sterol 14-demethylase |
| Uniprot ID | Q9SAA9 |
| EC Number | 1.14.14.154 |
| Gene ID | 837712 |
| Species | Arabidopsis thaliana (Mouse-ear cress) |
| Txid | 3702 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O → C29H46O |
| Reaction Type | Decomposition |
| Chemical Bond | CH2 |
CYP51G1
Substrate Information:
| Substrate Name | Obtusifoliol |
| Substrate Chemical Formula | C30H50O |
| Substrate PubChem CID | 65252 |
| Substrate Smiles | C[C@H]1[C@@H]2CCC3=C([C@]2(CC[C@@H]1O)C)CC[C@]4([C@]3(CC[C@@H]4[C@H](C)CCC(=C)C(C)C)C)C |
| Substrate Structure |
Product Information:
| Product Name | 4Alpha-Methyl-Ergost-8,14,24(24′)-Trien-3Beta-Ol |
| Product Chemical Formula | C29H46O |
| Product PubChem CID | 60123239 |
| Product Smiles | C1C[C@@](C)2C3CC[C@@](C)4C([C@H](C)CCC(=C)C(C)C)CC=C4C=3CCC2[C@H](C)[C@H]1O |
| Product Structure |
References:
| Title: | Obtusifoliol 14alpha-demethylase (CYP51) antisense Arabidopsis shows slow growth and long life. |
| PMID: | 11437378 |
| Journal: | Biochemical and biophysical research communications |
| Year: | 2001/7/6 |