Detail Information

P450 Protein:

P450 SymbolCYP716Y1
Protein NameCYP716Y1
Uniprot IDW0FW87
SpeciesBupleurum falcatum (Sickle-leaved hare's-ear)
Txid 46367
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H50O → C30H50O2
Reaction TypeOxidation
Chemical BondCH2

Alpha-Amyrin

CYP716Y1

16Alpha-Hydroxy-Alpha-Amyrin

Substrate Information:

Substrate Name Alpha-Amyrin
Substrate Chemical FormulaC30H50O
Substrate PubChem CID73170
Substrate SmilesC[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C
Substrate Structure

Product Information:

Product Name 16Alpha-Hydroxy-Alpha-Amyrin
Product Chemical FormulaC30H50O2
Product Smiles[C@@H](C)1[C@H](C)CC[C@@](C)2[C@H](O)C[C@](C)3[C@@](C)4CCC5[C@](C)(C)[C@@H](O)CC[C@]5(C)C4CC=C3C12
Product Structure

References:

Title: Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum.
PMID: 24434554
Journal: Proceedings of the National Academy of Sciences of the United States of America
Year: 2014/1/28

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics