Detail Information
P450 Protein:
| P450 Symbol | CYP716A12 |
| Protein Name | Beta-amyrin 28-monooxygenase |
| Uniprot ID | Q2MJ20 |
| EC Number | 1.14.14.126 |
| Gene ID | 25502252 |
| Species | Medicago truncatula (Barrel medic) (Medicago tribuloides) |
| Txid | 3880 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O2 → C30H48O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP716A12
Substrate Information:
| Substrate Name | 16Alpha-Hydroxy-Beta-Amyrin |
| Substrate Chemical Formula | C30H50O2 |
| Substrate PubChem CID | 131841473 |
| Substrate Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@H]([C@@]5([C@H]4CC(CC5)(C)C)C)O)C)C)(C)C)O |
| Substrate Structure |
Product Information:
| Product Name | Echinocystic Acid |
| Product Chemical Formula | C30H48O4 |
| Product PubChem CID | 73309 |
| Product Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@H]([C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)O)C)C)(C)C)O |
| Product Structure |
References:
| Title: | Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum. |
| PMID: | 24434554 |
| Journal: | Proceedings of the National Academy of Sciences of the United States of America |
| Year: | 2014/1/28 |