Detail Information
P450 Protein:
| P450 Symbol | CYP76AH15 |
| Protein Name | Cytochrome P450 CYP76AH15 |
| Uniprot ID | A0A1B0VRQ0 |
| Species | Plectranthus barbatus |
| Txid | 41228 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H34O → C20H32O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP76AH15
Substrate Information:
| Substrate Name | (13R)-8,13-epoxylabd-14-ene |
| Substrate Chemical Formula | C20H34O |
| Substrate PubChem CID | 10085645 |
| Substrate Smiles | C[C@@]1(CCC2[C@]3(CCCC(C3CC[C@]2(O1)C)(C)C)C)C=C |
| Substrate Structure |
Product Information:
| Product Name | (3R,4aR,10aS)-3,4a,7,7,10a-pentamethyl-3-vinyl-2,3,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-1H-cyclohexa[1,2-f]chromen-1-one |
| Product Chemical Formula | C20H32O2 |
| Product Smiles | C=C[C@@](C)1O[C@@]2(CCC3[C@](CCCC3(C)C)(C2C(=O)C1)C)C |
| Product Structure |
References:
| Title: | Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii. |
| PMID: | 28290983 |
| Journal: | eLife |
| Year: | 2017/3/14 |