Detail Information

P450 Protein:

P450 SymbolCYP716A355
Protein Name
Uniprot ID
SpeciesAralia elata
Txid 82095
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
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Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H48O4 → C30H48O5
Reaction TypeOxidation
Chemical BondCH

6-OH oleanolic acid

CYP716A355

6-OH echinocystic acid

Substrate Information:

Substrate Name 6-OH oleanolic acid
Substrate Chemical FormulaC30H48O4
Substrate PubChem CID9982268
Substrate SmilesC[C@]12CC[C@@H](C(C1[C@@H](C[C@@]3(C2CC=C4[C@]3(CC[C@@]5(C4CC(CC5)(C)C)C(=O)O)C)C)O)(C)C)O
Substrate Structure

Product Information:

Product Name 6-OH echinocystic acid
Product Chemical FormulaC30H48O5
Product Smiles[C@@H](O)1CC[C@@](C)2C3CC=C4C5[C@](C(O)=O)(CC[C@@](C)(C)C5)[C@@H](O)C[C@]4([C@]3(C)C[C@@H](O)C2[C@]1(C)C)C
Product Structure

References:

Title: Exploring oxidosqualene cyclases and cytochrome P450s from Aralia elata for the synthesis of diverse pentacyclic triterpene sapogenins in Nicotiana benthamiana.
PMID: 40435688
Journal: Plant Physiol Biochem
Year: 2025/5/19

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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