Detail Information

P450 Protein:

P450 SymbolCYP716A355
Protein Name
Uniprot ID
SpeciesAralia elata
Txid 82095
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H48O3 → C30H48O4
Reaction TypeOxidation
Chemical BondCH

Oleanolic Acid

CYP716A355

Echinocystic acid

Substrate Information:

Substrate Name Oleanolic Acid
Substrate Chemical FormulaC30H48O3
Substrate PubChem CID10494
Substrate SmilesC[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O
Substrate Structure

Product Information:

Product Name Echinocystic acid
Product Chemical FormulaC30H48O4
Product PubChem CID6708654
Product SmilesC[C@]12CC[C@@H](C(C1CC[C@@]3(C2CC=C4[C@]3(C[C@@H]([C@@]5(C4CC(CC5)(C)C)C(=O)O)O)C)C)(C)C)O
Product Structure

References:

Title: Exploring oxidosqualene cyclases and cytochrome P450s from Aralia elata for the synthesis of diverse pentacyclic triterpene sapogenins in Nicotiana benthamiana.
PMID: 40435688
Journal: Plant Physiol Biochem
Year: 2025/5/19

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics