Detail Information

P450 Protein:

P450 SymbolCYP716A296
Protein Name
Uniprot ID
SpeciesAralia elata
Txid 82095
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H50O3 → C30H48O5
Reaction TypeOxidation
Chemical BondCH

6,16-OH beta-amyrin

CYP716A296

6-OH echinocystic acid

Substrate Information:

Substrate Name 6,16-OH beta-amyrin
Substrate Chemical FormulaC30H50O3
Substrate Smiles[C@@H](O)1CC[C@@](C)2C3CC=C4C5[C@](C)(CC[C@@](C)(C)C5)[C@@H](O)C[C@]4([C@]3(C)C[C@@H](O)C2[C@]1(C)C)C
Substrate Structure

Product Information:

Product Name 6-OH echinocystic acid
Product Chemical FormulaC30H48O5
Product Smiles[C@@H](O)1CC[C@@](C)2C3CC=C4C5[C@](C(O)=O)(CC[C@@](C)(C)C5)[C@@H](O)C[C@]4([C@]3(C)C[C@@H](O)C2[C@]1(C)C)C
Product Structure

References:

Title: Exploring oxidosqualene cyclases and cytochrome P450s from Aralia elata for the synthesis of diverse pentacyclic triterpene sapogenins in Nicotiana benthamiana.
PMID: 40435688
Journal: Plant Physiol Biochem
Year: 2025/5/19

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics