Detail Information
P450 Protein:
| P450 Symbol | CYP736A |
| Protein Name | Cytochrome P450 CYP736A |
| Uniprot ID | |
| Species | Angelica sinensis |
| Txid | 165353 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C14H14O3 → C14H14O4 |
| Reaction Type | Cyclization |
| Chemical Bond |
CYP736A
Substrate Information:
| Substrate Name | 7-demethylsuberosin |
| Substrate Chemical Formula | C14H14O3 |
| Substrate Smiles | O1C(C=CC2=CC(=C(C=C12)O)C/C=C(C)/C)=O |
| Substrate Structure |
Product Information:
| Product Name | Marmesin |
| Product Chemical Formula | C14H14O4 |
| Product PubChem CID | 334704 |
| Product CAS Number | 13849-08-6 |
| Product Smiles | CC(C)([C@@H]1CC2=C(O1)C=C3C(=C2)C=CC(=O)O3)O |
| Product Structure |
References:
| Title: | Integrative multi-omics data provide insights into the biosynthesis of furanocoumarins and mechanisms regulating their accumulation in Angelica dahurica. |
| PMID: | 40269101 |
| Journal: | communications biology |
| Year: | 2025/4/23 |