Detail Information
P450 Protein:
| P450 Symbol | CYP150 |
| Protein Name | |
| Uniprot ID | |
| Species | Gongronemopsis tenacissima |
| Txid | 187505 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | GenebankID:OR727879.1 |
Reaction Scheme:
| Chemical Conversion | C27H46O → C21H32O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP150
Substrate Information:
| Substrate Name | Cholesterol |
| Substrate Chemical Formula | C27H46O |
| Substrate PubChem CID | 5997 |
| Substrate Smiles | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C |
| Substrate Structure |
Product Information:
| Product Name | Pregnenolone |
| Product Chemical Formula | C21H32O2 |
| Product PubChem CID | 8955 |
| Product CAS Number | 145-13-1 |
| Product Smiles | CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C |
| Product Structure |
References:
| Title: | Elucidation of the plant progesterone biosynthetic pathway and its application in a yeast cell factory. |
| PMID: | 40157715 |
| Journal: | Metabolic Engineering |
| Year: | 2025/3/27 |