Detail Information
P450 Protein:
| P450 Symbol | CYP72A1139 |
| Protein Name | cytochrome P450 CYP72A1139 |
| Uniprot ID | |
| Species | Hedera helix |
| Txid | 4052 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | Protein id:XIF85664.1 |
Reaction Scheme:
| Chemical Conversion | C30H48O4 → C30H48O5 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP72A1139
Substrate Information:
| Substrate Name | Hederagenin |
| Substrate Chemical Formula | C30H48O4 |
| Substrate PubChem CID | 73299 |
| Substrate Smiles | C[C@]12CC[C@@H]([C@@]([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)CO)O |
| Substrate Structure |
Product Information:
| Product Name | 16-OH-hederagenin |
| Product Chemical Formula | C30H48O5 |
| Product Smiles | C[C@@]12[C@H]3CC=C4[C@@H]5CC(C)(C)CC[C@]5(C(O)=O)C(O)C[C@]4([C@]3(C)CC[C@H]1[C@@](CO)(C)[C@@H](O)CC2)C |
| Product Structure |
References:
| Title: | Integrated metabolome and transcriptome analyses revealed key cytochrome P450 genes involved in the biosynthesis of oleanane-type saponins in Hedera helix L. |
| PMID: | 40147328 |
| Journal: | Plant Physiology and Biochemistry |
| Year: | 2025/3/21 |