P450 Protein:
| P450 Symbol | CYP116B234 |
| Protein Name | self‐sufficient P450 CYP116B234 |
| Uniprot ID | |
| Species | Rhodococcus globerulus |
| Txid | 33008 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | GenebankID:MCE4265947.1 |
Reaction Scheme:
| Chemical Conversion | C8H8O3 → C8H8O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP116B234
Substrate Information:
| Substrate Name | (2-Hydroxyphenyl)acetic acid |
| Substrate Chemical Formula | C8H8O3 |
| Substrate PubChem CID | 11970 |
| Substrate Smiles | C1=CC=C(C(=C1)CC(=O)O)O |
| Substrate Structure |
Product Information:
| Product Name | Homogentisic Acid |
| Product Chemical Formula | C8H8O4 |
| Product PubChem CID | 780 |
| Product Smiles | C1=CC(=C(C=C1O)CC(=O)O)O |
| Product Structure |
References:
| Title: | Characterisation of the Self-Sufficient Cytochrome P450 CYP116B234 From Rhodococcus globerulus and Its Suggested Native Role in 2-Hydroxyphenylacetic Acid Metabolism. |
| PMID: | 40056075 |
| Journal: | Microb Biotechnol |
| Year: | 2025/3/8 |