Detail Information
P450 Protein:
| P450 Symbol | CYP94D108 |
| Protein Name | Cytochrome P450 CYP94D108 |
| Uniprot ID | A0A517FNC7 |
| Species | Paris polyphylla (Daiswa polyphylla) |
| Txid | 49666 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C27H46O2 → C27H42O3 |
| Reaction Type | Cyclization |
| Chemical Bond |
CYP94D108
Substrate Information:
| Substrate Name | 22R-Hydroxycholesterol |
| Substrate Chemical Formula | C27H46O2 |
| Substrate PubChem CID | 167685 |
| Substrate Smiles | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)[C@@H](CCC(C)C)O |
| Substrate Structure |
Product Information:
| Product Name | Diosgenin |
| Product Chemical Formula | C27H42O3 |
| Product PubChem CID | 99474 |
| Product CAS Number | 512-04-9 |
| Product Smiles | C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1 |
| Product Structure |
References:
| Title: | Characterization of a 4'-O-rhamnosyltransferase and de novo biosynthesis of bioactive steroidal triglycosides from Paris polyphylla. |
| PMID: | 39844466 |
| Journal: | Plant Communications |
| Year: | 2025/1/22 |