P450 Protein:

P450 Symbol	CYP2C8
Protein Name	Cytochrome P450 2C8
Uniprot ID	P10632
EC Number	1.14.14.1
Gene ID	1558
Species	Homo sapiens (Human)
Txid	9606
P450 Protein Structure	Go to AlphaFold Website Model Confidence (pLDDT) Very high (>90) High (90 > 70) Low (70 > 50) Very low (<50) Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence	GO

Reaction Scheme:

Chemical Conversion	C47H51NO14 → C47H51NO15
Reaction Type	Oxidation
Chemical Bond	CH

Substrate Information:

Substrate Name	Paclitaxel
Substrate Chemical Formula	C47H51NO14
Substrate PubChem CID	36314
Substrate Smiles	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Substrate Structure	Download SDF

Product Information:

Product Name	6-Hydroxytaxol
Product Chemical Formula	C47H51NO15
Product PubChem CID	10056458
Product CAS Number	153212-75-0
Product Smiles	CC1=C2[C@H](C(=O)[C@]3([C@H]([C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C4=CC=CC=C4)NC(=O)C5=CC=CC=C5)O)O)OC(=O)C6=CC=CC=C6)[C@@]7(CO[C@@H]7[C@H]([C@@H]3O)O)OC(=O)C)C)OC(=O)C
Product Structure	Download SDF

References: