P450 Protein:

P450 Symbol	CYP3A4
Protein Name	Cytochrome P450 3A4
Uniprot ID	P08684
EC Number	1.14.14.1; 1.14.14.55; 1.14.14.56; 1.14.14.73
Gene ID	1576
Species	Homo sapiens (Human)
Txid	9606
P450 Protein Structure	Go to AlphaFold Website Model Confidence (pLDDT) Very high (>90) High (90 > 70) Low (70 > 50) Very low (<50) Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence	GO

Reaction Scheme:

Chemical Conversion	C47H51NO14 → C47H51NO15
Reaction Type	Oxidation
Chemical Bond	CH

Substrate Information:

Substrate Name	Paclitaxel
Substrate Chemical Formula	C47H51NO14
Substrate PubChem CID	36314
Substrate Smiles	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Substrate Structure	Download SDF

Product Information:

Product Name	3′-p-Hydroxypaclitaxel
Product Chemical Formula	C47H51NO15
Product PubChem CID	3081785
Product CAS Number	132160-32-8
Product Smiles	CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=C(C=C5)O)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Product Structure	Download SDF

References: