Detail Information
P450 Protein:
| P450 Symbol | CYP80Q5 |
| Protein Name | |
| Uniprot ID | |
| Species | Stephania tetrandra |
| Txid | 425106 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C17H19NO3 → C17H17NO3 |
| Reaction Type | Cyclization |
| Chemical Bond |
CYP80Q5
Substrate Information:
| Substrate Name | Coclaurine |
| Substrate Chemical Formula | C17H19NO3 |
| Substrate PubChem CID | 160487 |
| Substrate Smiles | COC1=C(C=C2[C@@H](NCCC2=C1)CC3=CC=C(C=C3)O)O |
| Substrate Structure |
Product Information:
| Product Name | (R)-crotoflorine |
| Product Chemical Formula | C17H17NO3 |
| Product PubChem CID | 131841576 |
| Product Smiles | COC1=C(C2=C3[C@@H](CC24C=CC(=O)C=C4)NCCC3=C1)O |
| Product Structure |
References:
| Title: | Identification of the cytochrome P450s responsible for the biosynthesis of two types of aporphine alkaloids and their de novo biosynthesis in yeast. |
| PMID: | 38953746 |
| Journal: | J Integr Plant Biol |
| Year: | 2024/7/2 |