Detail Information
P450 Protein:
| P450 Symbol | CYP719C4 |
| Protein Name | |
| Uniprot ID | |
| Species | Stephania tetrandra |
| Txid | 425106 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C19H21NO4 → C19H19NO4 |
| Reaction Type | Cyclization |
| Chemical Bond |
CYP719C4
Substrate Information:
| Substrate Name | (+)-Boldine |
| Substrate Chemical Formula | C19H21NO4 |
| Substrate PubChem CID | 10154 |
| Substrate Smiles | CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC(=C(C=C43)OC)O)OC)O |
| Substrate Structure |
Product Information:
| Product Name | (+)-Isodomesticine |
| Product Chemical Formula | C19H19NO4 |
| Product PubChem CID | 15690954 |
| Product CAS Number | 70560-83-7 |
| Product Smiles | CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC5=C(C=C43)OCO5)OC)O |
| Product Structure |
References:
| Title: | Identification of the cytochrome P450s responsible for the biosynthesis of two types of aporphine alkaloids and their de novo biosynthesis in yeast. |
| PMID: | 38953746 |
| Journal: | J Integr Plant Biol |
| Year: | 2024/7/2 |