Detail Information

P450 Protein:

P450 SymbolA09437
Protein NameP450FE
Uniprot ID
SpeciesFusarium equiseti HG18
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
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Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C24H40O3 → C24H40O4
Reaction TypeOxidation
Chemical BondCH

Lithocholic Acid

A09437

Ursodeoxycholic Acid

Substrate Information:

Substrate Name Lithocholic Acid
Substrate Chemical FormulaC24H40O3
Substrate PubChem CID9903
Substrate SmilesC[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C
Substrate Structure

Product Information:

Product Name Ursodeoxycholic Acid
Product Chemical FormulaC24H40O4
Product PubChem CID31401
Product CAS Number128-13-2
Product SmilesC[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C
Product Structure

References:

Title: A fungal P450 enzyme from Fusarium equiseti HG18 with 7β-hydroxylase activity in biosynthesis of ursodeoxycholic acid.
PMID: 38508471
Journal: The Journal of Steroid Biochemistry and Molecular Biology
Year: 2024/4/18

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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