Detail Information
P450 Protein:
| P450 Symbol | CYP71BE52 |
| Protein Name | Salviol synthase |
| Uniprot ID | A0A0S1TQ04 |
| EC Number | 1.14.14.62 |
| Species | Salvia pomifera (Apple sage) |
| Txid | 396869 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H30O2 → C20H30O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP71BE52
Substrate Information:
| Substrate Name | Abietic acid |
| Substrate Chemical Formula | C20H30O2 |
| Substrate PubChem CID | 10569 |
| Substrate Smiles | C[C@@]12[C@]([C@@](C(O)=O)(C)CCC1)(CC=C3[C@@]2(CCC(C(C)C)=C3)[H])[H] |
| Substrate Structure |
Product Information:
| Product Name | (1R,3R,4aR,4bR,10aR)-3-hydroxy-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthrene-1-carboxylic acid |
| Product Chemical Formula | C20H30O3 |
| Product PubChem CID | 101775561 |
| Product Smiles | CC(C)C1=CC2=CC[C@@H]3[C@@]([C@H]2CC1)(C[C@H](C[C@@]3(C)C(=O)O)O)C |
| Product Structure |
References:
| Title: | Combinatorial biosynthesis in yeast leads to over 200 diterpenoids. |
| PMID: | 38387676 |
| Journal: | Metabolic Engineering |
| Year: | 2024/2/20 |