Detail Information

P450 Protein:

P450 SymbolCYP720B4
Protein NameCYP720B4
Uniprot IDE5FA70
SpeciesPicea sitchensis (Sitka spruce) (Pinus sitchensis)
Txid 3332
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C20H32 → C20H30O2
Reaction TypeOxidation
Chemical BondCH

Miltiradiene

CYP720B4

(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,5,8,9,10,10a-octahydrophenanthrene-1-carboxylic acid

Substrate Information:

Substrate Name Miltiradiene
Substrate Chemical FormulaC20H32
Substrate PubChem CID20837867
Substrate SmilesCC(C)C1=CCC2=C(C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C
Substrate Structure

Product Information:

Product Name (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,5,8,9,10,10a-octahydrophenanthrene-1-carboxylic acid
Product Chemical FormulaC20H30O2
Product PubChem CID67858350
Product SmilesCC(C)C1=CCC2=C(C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)O)C
Product Structure

References:

Title: Combinatorial biosynthesis in yeast leads to over 200 diterpenoids.
PMID: 38387676
Journal: Metabolic Engineering
Year: 2024/2/20

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics