Detail Information
P450 Protein:
| P450 Symbol | CYP76M8 |
| Protein Name | Oryzalexin D synthase |
| Uniprot ID | Q6YTF1 |
| EC Number | 1.14.14.112; 1.14.14.123 |
| Gene ID | 4329722 |
| Species | Oryza sativa subsp. japonica (Rice) |
| Txid | 39947 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H32 → C20H32O |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP76M8
Substrate Information:
| Substrate Name | (4aS,5S,8aS)-1,1,4a-trimethyl-6-methylidene-5-[(2E)-3-methylpenta-2,4-dienyl]decahydronaphthalene |
| Substrate Chemical Formula | C20H32 |
| Substrate Smiles | [H][C@@]12CCC(=C)[C@@H]([C@]1(CCC[C@@]2(C)C)C)C/C=C(C)/C=C |
| Substrate Structure |
Product Information:
| Product Name | (2S,4aS,4R,8aS)-4a,8,8-trimethyl-3-methylidene-4-[(2E)-3-methylpenta-2,4-dienyl]decahydronaphthalen-2-ol |
| Product Chemical Formula | C20H32O |
| Product Smiles | [H][C@@]12C[C@H](O)C(=C)[C@@H]([C@]1(CCC[C@@]2(C)C)C)C/C=C(C)/C=C |
| Product Structure |
References:
| Title: | Combinatorial biosynthesis in yeast leads to over 200 diterpenoids. |
| PMID: | 38387676 |
| Journal: | Metabolic Engineering |
| Year: | 2024/2/20 |