Detail Information
P450 Protein:
| P450 Symbol | CYP102A1 |
| Protein Name | CYP102A1 variant M179 |
| Uniprot ID | |
| Species | Priestia megaterium |
| Txid | 1348623 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | Mutations versus WT:R47L/F81I/F87V/E143G/L188Q/N213S/E267V |
Reaction Scheme:
| Chemical Conversion | C10H18O → C10H18O2 |
| Reaction Type | Oxidation |
| Chemical Bond | C=C |
CYP102A1
Substrate Information:
| Substrate Name | Terpinen-4-ol |
| Substrate Chemical Formula | C10H18O |
| Substrate PubChem CID | 11230 |
| Substrate Smiles | CC1=CCC(CC1)(C(C)C)O |
| Substrate Structure |
Product Information:
| Product Name | 1,4-dihydroxy-p-menth-2-ene |
| Product Chemical Formula | C10H18O2 |
| Product PubChem CID | 300085 |
| Product CAS Number | 40735-19-1 |
| Product Smiles | CC(C)C1(CCC(C=C1)(C)O)O |
| Product Structure |
References:
| Title: | Production of Mono-Hydroxylated Derivatives of Terpinen-4-ol by Bacterial CYP102A1 Enzymes. |
| PMID: | 38044690 |
| Journal: | J Microbiol Biotechnol |
| Year: | 2023/11/1 |