Detail Information
P450 Protein:
| P450 Symbol | CYP102A1 |
| Protein Name | Cytochrome P450-BM3 variant P411-PFA |
| Uniprot ID | |
| Species | Priestia megaterium |
| Txid | 1348623 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | UniRef ID:UPI0023AB5709 |
Reaction Scheme:
| Chemical Conversion | C10H16O → C12H17F3O |
| Reaction Type | Cyclization |
| Chemical Bond | C=C |
CYP102A1
Substrate Information:
| Substrate Name | Carveol |
| Substrate Chemical Formula | C10H16O |
| Substrate PubChem CID | 7438 |
| Substrate Smiles | CC1=CCC(CC1O)C(=C)C |
| Substrate Structure |
Product Information:
| Product Name | L-carveol |
| Product Chemical Formula | C12H17F3O |
| Product Smiles | OC1CC(CC=C1C)C1(C(C(F)(F)F)C1)C |
| Product Structure |
References:
| Title: | Synthesis of Trifluoromethylated Monoterpenes by an Engineered Cytochrome P450. |
| PMID: | 38012074 |
| Journal: | Chemistry |
| Year: | 2023/11/27 |