Detail Information

P450 Protein:

P450 SymbolPanH
Protein Name
Uniprot ID
SpeciesPanus rudis
Txid 48022
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO
RemarksGenBank: WJQ78194.1

Reaction Scheme:

Chemical Conversion C11H14O3 → C11H14O4
Reaction TypeOxidation
Chemical BondC=C

2-[(1S)-1-hydroxy-3-methylbut-2-enyl]benzene-1,4-diol

PanH

(1aS,5aS,5R)-5-hydroxy-3-[(1S)-1-hydroxy-3-methylbut-2-enyl]-1a,2,5,5a-tetrahydrocyclohexa[1,2-b]oxiren-2-one

Substrate Information:

Substrate Name 2-[(1S)-1-hydroxy-3-methylbut-2-enyl]benzene-1,4-diol
Substrate Chemical FormulaC11H14O3
Substrate SmilesOC1C=CC(=CC=1[C@H](/C=C(/C)C)O)O
Substrate Structure

Product Information:

Product Name (1aS,5aS,5R)-5-hydroxy-3-[(1S)-1-hydroxy-3-methylbut-2-enyl]-1a,2,5,5a-tetrahydrocyclohexa[1,2-b]oxiren-2-one
Product Chemical FormulaC11H14O4
Product SmilesO=C1C([C@H](/C=C(/C)C)O)=C[C@H]([C@H]2[C@@H]1O2)O
Product Structure

References:

Title: A Mushroom P450-Monooxygenase Enables Regio- and Stereoselective Biocatalytic Synthesis of Epoxycyclohexenones.
PMID: 37852936
Journal: Angew Chem Int Ed Engl
Year: 2023/10/31

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics