Detail Information
P450 Protein:
| P450 Symbol | OsdM |
| Protein Name | |
| Uniprot ID | |
| Species | Fusarium oxysporum |
| Txid | 5507 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C29H44NO5 → C29H44NO6 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
OsdM
Substrate Information:
| Substrate Name | 3-{6-[(2Z,5R,7S)-5,7-dimethylnon-2-en-2-yl]-5-methyl-3,4,5,6-tetrahydro-2H-pyran-2-yl}-4-hydroxy-5-(1-hydroxy-4-oxocyclohexyl)-1-methyl-1,2-dihydropyridin-2-one |
| Substrate Chemical Formula | C29H44NO5 |
| Substrate Smiles | C([H])(/C(=CC[C@H](C)C[C@@H](C)CC)/C)1C([H])(CCC(C2=C(C(C(O)3CCC(CC3)=O)=CN(C)C2=O)O)([H])O1)C |
| Substrate Structure |
Product Information:
| Product Name | 3-{6-[(2Z,5R,7S)-5,7-dimethylnon-2-en-2-yl]-5-methyl-3,4,5,6-tetrahydro-2H-pyran-2-yl}-5-[(1S,2S)-1,2-dihydroxy-4-oxocyclohexyl]-4-hydroxy-1-methyl-1,2-dihydropyridin-2-one |
| Product Chemical Formula | C29H44NO6 |
| Product Smiles | C([H])(/C(=CC[C@H](C)C[C@@H](C)CC)/C)1C([H])(CCC(C2=C(C([C@](O)3CCC(C[C@@H]3O)=O)=CN(C)C2=O)O)([H])O1)C |
| Product Structure |
References:
| Title: | Elucidation of a Dearomatization Route in the Biosynthesis of Oxysporidinone Involving a TenA-like Cytochrome P450 Enzyme. |
| PMID: | 37086399 |
| Journal: | Angew Chem Int Ed Engl |
| Year: | 2023/5/9 |