Detail Information
P450 Protein:
| P450 Symbol | CYP82M3 |
| Protein Name | CYP82M3 |
| Uniprot ID | A0A9Y1E1K8 |
| Species | Datura stramonium |
| Txid | 4076 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C9H15NO3 → C8H13NO |
| Reaction Type | Cyclization |
| Chemical Bond |
CYP82M3
Substrate Information:
| Substrate Name | 4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate |
| Substrate Chemical Formula | C9H15NO3 |
| Substrate PubChem CID | 57417332 |
| Substrate Smiles | CN1CCCC1CC(=O)CC(=O)O |
| Substrate Structure |
Product Information:
| Product Name | Tropinone |
| Product Chemical Formula | C8H13NO |
| Product PubChem CID | 446337 |
| Product CAS Number | 532-24-1 |
| Product Smiles | CN1[C@@H]2CC[C@H]1CC(=O)C2 |
| Product Structure |
References:
| Title: | Revealing evolution of tropane alkaloid biosynthesis by analyzing two genomes in the Solanaceae family. |
| PMID: | 36922496 |
| Journal: | Nature communications |
| Year: | 2023/3/15 |