Detail Information
P450 Protein:
| P450 Symbol | CYP68J5_fg |
| Protein Name | Cytochrome P450 CYP68J5 |
| Uniprot ID | |
| Species | Fusarium graminearum |
| Txid | 5518 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | GenBank: OP854625.1 |
Reaction Scheme:
| Chemical Conversion | C21H30O2 → C21H30O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP68J5_fg
Substrate Information:
| Substrate Name | Progesterone |
| Substrate Chemical Formula | C21H30O2 |
| Substrate PubChem CID | 5994 |
| Substrate Smiles | CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C |
| Substrate Structure |
Product Information:
| Product Name | 15alpha-Hydroxyprogesterone |
| Product Chemical Formula | C21H30O3 |
| Product Smiles | O=C([C@H]1C[C@H](O)C2[C@@]1(CCC1[C@]3(CCC(C=C3CCC21)=O)C)C)C |
| Product Structure |
References:
| Title: | A Fungal P450 Enzyme from Fusarium graminearum with Unique 12β-Steroid Hydroxylation Activity. |
| PMID: | 36853033 |
| Journal: | Appl Environ Microbiol |
| Year: | 2023/2/28 |