Detail Information
P450 Protein:
| P450 Symbol | CYP80Q2 |
| Protein Name | (S)-N-methylcoclaurine 3'-hydroxylase isozyme 2 |
| Uniprot ID | |
| Species | Nelumbo nucifera |
| Txid | 4432 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | GenBank:XM_010255687 |
Reaction Scheme:
| Chemical Conversion | C18H21NO3 → C36H40N2O6 |
| Reaction Type | Polymerization |
| Chemical Bond |
CYP80Q2
Substrate Information:
| Substrate Name | N-Methylcoclaurine |
| Substrate Chemical Formula | C18H21NO3 |
| Substrate PubChem CID | 2752274 |
| Substrate Smiles | CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)O)O)OC |
| Substrate Structure |
Product Information:
| Product Name | Nelumboferine |
| Product Chemical Formula | C36H40N2O6 |
| Product PubChem CID | 76046684 |
| Product Smiles | CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)O)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)O)O)OC |
| Product Structure |
References:
| Title: | Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). |
| PMID: | 36805479 |
| Journal: | Sci Rep |
| Year: | 2023/2/20 |