Detail Information
P450 Protein:
| P450 Symbol | CYP719A22 |
| Protein Name | |
| Uniprot ID | |
| Species | Nelumbo nucifera |
| Txid | 4432 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | GenBank:XM_010268782 |
Reaction Scheme:
| Chemical Conversion | C17H17NO2 → C17H15NO2 |
| Reaction Type | Cyclization |
| Chemical Bond |
CYP719A22
Substrate Information:
| Substrate Name | Caaverine |
| Substrate Chemical Formula | C17H17NO2 |
| Substrate PubChem CID | 23335 |
| Substrate Smiles | COC1=C(C2=C3[C@@H](CC4=CC=CC=C42)NCCC3=C1)O |
| Substrate Structure |
Product Information:
| Product Name | Anonaine |
| Product Chemical Formula | C17H15NO2 |
| Product PubChem CID | 160597 |
| Product CAS Number | 1862-41-5 |
| Product Smiles | C1CN[C@@H]2CC3=CC=CC=C3C4=C2C1=CC5=C4OCO5 |
| Product Structure |
References:
| Title: | Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). |
| PMID: | 36805479 |
| Journal: | Sci Rep |
| Year: | 2023/2/20 |