Detail Information
P450 Protein:
| P450 Symbol | CYP80B3 |
| Protein Name | N-methylcoclaurine 3'-hydroxylase |
| Uniprot ID | Q9SP06 |
| EC Number | 1.14.14.102 |
| Species | Papaver somniferum |
| Txid | 3469 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C18H21NO3 → C18H21NO4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP80B3
Substrate Information:
| Substrate Name | N-Methylcoclaurine |
| Substrate Chemical Formula | C18H21NO3 |
| Substrate PubChem CID | 2752274 |
| Substrate Smiles | CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)O)O)OC |
| Substrate Structure |
Product Information:
| Product Name | 3'-Hydroxy-N-methylcoclaurine |
| Product Chemical Formula | C18H21NO4 |
| Product PubChem CID | 5117623 |
| Product Smiles | O(C)C1=C(O)C=C2C(CC3C=CC(O)=C(O)C=3)N(C)CCC2=C1 |
| Product Structure |
References:
| Title: | Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somninferum. |
| PMID: | 10724180 |
| Journal: | Phytochemistry |
| Year: | 2000/3/ |