Detail Information
P450 Protein:
| P450 Symbol | oleP |
| Protein Name | Cytochrome P-450 |
| Uniprot ID | Q59819 |
| Species | Streptomyces antibioticus |
| Txid | 1890 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C24H40O3 → C24H40O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
| Transformations | 1.Hydroxylation at an Aromatic Carbon |
oleP
Substrate Information:
| Substrate Name | Lithocholic acid |
| Substrate Chemical Formula | C24H40O3 |
| Substrate PubChem CID | 9903 |
| Substrate Smiles | O=C(O)CCC(C)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C |
| Substrate Structure |
Product Information:
| Product Name | Deoxycholic acid |
| Product Chemical Formula | C24H40O4 |
| Product PubChem CID | 222528 |
| Product CAS Number | 83-44-3 |
| Product Smiles | O=C(O)CCC(C)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C |
| Product Structure |
References:
| Title: | 利用大肠杆菌P450酶全细胞催化合成羟基化脱氧胆酸的方法及应用 |
| Patent ID: | CN117487727 |
| Journal: | |
| Year: | 2024/2/2 |