Detail Information
P450 Protein:
| P450 Symbol | CYP199A2 |
| Protein Name | Cytochrome p450 CYP199A2 |
| Uniprot ID | Q6N8N2 |
| EC Number | 1.14.99.15 |
| Gene ID | 66892909 |
| Species | Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) |
| Txid | 258594 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C11H8O3 → C11H8O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Conditions | 180 min |
| Transformations | 1.Hydroxylation of Aromatic Compounds 2.Hydroxylation at an Aromatic Carbon |
CYP199A2
Substrate Information:
| Substrate Name | 6-Hydroxy-2-naphthoic acid |
| Substrate Chemical Formula | C11H8O3 |
| Substrate PubChem CID | 85557 |
| Substrate Smiles | C1=CC2=C(C=CC(=C2)O)C=C1C(=O)O |
| Substrate Structure |
Product Information:
| Product Name | 6,7-dihydroxynaphthalene-2-carboxylic acid |
| Product Chemical Formula | C11H8O4 |
| Product PubChem CID | 466853 |
| Product CAS Number | 113458-95-0 |
| Product Smiles | C1=CC(=CC2=CC(=C(C=C21)O)O)C(=O)O |
| Product Structure |
References:
| Title: | Biocatalytic synthesis of dihydroxynaphthoic acids by cytochrome P450 CYP199A2. |
| PMID: | 19966465 |
| Journal: | Bioscience, Biotechnology, and Biochemistry (2009) |
| Year: | 2009/12/7 |