Detail Information
P450 Protein:
| P450 Symbol | |
| Protein Name | P450cam-RhFRed_L3 |
| Uniprot ID | |
| Species | Rhodococcus sp. NCIMB 9784 |
| Txid | 157732 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C10H16O → C10H16O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
| Conditions | pH 7, 25°C |
Substrate Information:
| Substrate Name | D-(+)-Camphor |
| Substrate Chemical Formula | C10H16O |
| Substrate PubChem CID | 9543187 |
| Substrate Smiles | C1CC2C(C)(C)[C@]1(C)C(=O)C2 |
| Substrate Structure |
Product Information:
| Product Name | (1R,5R)-5-hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one |
| Product Chemical Formula | C10H16O2 |
| Product PubChem CID | 130832289 |
| Product Smiles | C1[C@@H](O)C2C(C)(C)[C@]1(C)C(=O)C2 |
| Product Structure |
References:
| Title: | Engineering and improvement of the efficiency of a chimeric [P450cam-RhFRed reductase domain] enzyme. |
| PMID: | 19532862 |
| Journal: | Chemical Communications (Cambridge, United Kingdom) (2009) |
| Year: | 2009/3/24 |