Detail Information
P450 Protein:
| P450 Symbol | CYP102A1 |
| Protein Name | P450 BM3 9-10A variant |
| Uniprot ID | |
| Species | Priestia megaterium (strain ATCC 14581 / DSM 32 / CCUG 1817 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / NRRL B-14308 / VKM B-512 / Ford 19) |
| Txid | 1348623 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
| Remarks | Mutations versus WT: R47C;V78A;K94I;P142S;T175I;A184V;F205C;S226R;H236Q;E252G;R255S;A290V;L353V |
Reaction Scheme:
| Chemical Conversion | C6H14 → C6H14O |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP102A1
Substrate Information:
| Substrate Name | Hexane |
| Substrate Chemical Formula | C6H14 |
| Substrate PubChem CID | 8058 |
| Substrate Smiles | CCCCCC |
| Substrate Structure |
Product Information:
| Product Name | 2-Hexanol |
| Product Chemical Formula | C6H14O |
| Product PubChem CID | 12297 |
| Product Smiles | CCCCC(C)O |
| Product Structure |
References:
| Title: | Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3. |
| PMID: | 14583039 |
| Journal: | World Intellectual Property Organization |
| Year: | 2003/11/5 |