Detail Information
P450 Protein:
| P450 Symbol | moxA |
| Protein Name | Cytochrome P450 type compactin 3'',4''-hydroxylase |
| Uniprot ID | Q2L6S8 |
| Gene ID | 5505085 |
| Species | Nonomuraea recticatena |
| Txid | 46178 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H48O3 → C30H48O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Water |
| Conditions | 20 h, pH 7.4, 30°C |
| Transformations | 1. Hydroxylation at an Aliphatic Carbon |
moxA
Substrate Information:
| Substrate Name | Oleanolic acid |
| Substrate Chemical Formula | C30H48O3 |
| Substrate PubChem CID | 10494 |
| Substrate Smiles | CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C |
| Substrate Structure |
Product Information:
| Product Name | Queretaroic acid |
| Product Chemical Formula | C30H48O4 |
| Product PubChem CID | 12314864 |
| Product CAS Number | 511-82-0 |
| Product Smiles | CC1(C2CCC3(C(C2(CCC1O)C)CC=C4C3(CCC5(C4CC(CC5)(C)CO)C(=O)O)C)C)C |
| Product Structure |
References:
| Title: | Hydroxylation of oleanolic acid to queretaroic acid by cytochrome P450 from Nonomuraea recticatena. |
| PMID: | 16960364 |
| Journal: | Bioscience, Biotechnology, and Biochemistry (2006) |
| Year: | 2006/9/7 |