Detail Information
P450 Protein:
| P450 Symbol | oxyB |
| Protein Name | p450 monooxygenase |
| Uniprot ID | A0A145YFZ5 |
| Gene ID | 66859936 |
| Species | Amycolatopsis coloradensis |
| Txid | 76021 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C45H53N7O11S → C45H53N9O11 |
| Reaction Type | Oxidation |
| Chemical Bond |
oxyB
Substrate Information:
| Substrate Name | N-Methyl-D-leucyl-D-tyrosyl-L-asparaginyl-(2R)-2-(4-hydroxyphenyl)glycyl-(2R)-2-(4-hydroxyphenyl)glycylthio-L-tyrosine |
| Substrate Chemical Formula | C45H53N7O11S |
| Substrate Smiles | O=C(N)CC(NC(=O)C(NC(=O)C(NC)CC(C)C)CC1=CC=C(O)C=C1)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)S)CC2=CC=C(O)C=C2)C3=CC=C(O)C=C3)C4=CC=C(O)C=C4 |
| Substrate Structure |
Product Information:
| Product Name | / |
| Product Chemical Formula | C45H53N9O11 |
| Product CAS Number | 943036-54-2 |
| Product Smiles | O=C(N)CC(NC(=O)C(NC(=O)C(NC)CC(C)C)CC1=CC=C(O)C=C1)C(=O)NC2C(=O)NC(C(=O)NC(C(=O)NN)CC3=CC=C(OC4=CC2=CC=C4O)C=C3)C5=CC=C(O)C=C5 |
| Product Structure |
References:
| Title: | An oxidative phenol coupling reaction catalyzed by oxyB, a cytochrome P450 from the vancomycin-producing microorganism. |
| PMID: | 15593150 |
| Journal: | Angewandte Chemie, International Edition (2004) |
| Year: | 2004/12/9 |