Detail Information
P450 Protein:
| P450 Symbol | Cyp2c29 |
| Protein Name | Cytochrome P450 2C29 |
| Uniprot ID | Q64458 |
| EC Number | 1.14.14.1 |
| Gene ID | 13095 |
| Species | Mus musculus |
| Txid | 10090 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C21H30O4 → C21H30O5 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Ethanol, Water |
| Conditions | 5 h, 28°C |
| Transformations | 1. Hydroxylation at an Aliphatic Carbon |
Cyp2c29
Substrate Information:
| Substrate Name | 11-Deoxycortisol |
| Substrate Chemical Formula | C21H30O4 |
| Substrate PubChem CID | 440707 |
| Substrate Smiles | CC12CCC(=O)C=C1CCC3C2CCC4(C3CCC4(C(=O)CO)O)C |
| Substrate Structure |
Product Information:
| Product Name | Cortisol |
| Product Chemical Formula | C21H30O5 |
| Product PubChem CID | 5754 |
| Product CAS Number | 50-23-7 |
| Product Smiles | CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O |
| Product Structure |
References:
| Title: | [Bioconversion of C19- and C21-steroids with parent and mutant strains of Curvularia lunata]. |
| PMID: | 20391766 |
| Journal: | Journal of Biotechnology (1998) |
| Year: | 1998/8/11 |