Detail Information
P450 Protein:
| P450 Symbol | CYP101A1 |
| Protein Name | Camphor 6-monooxygenase |
| Uniprot ID | P00183 |
| EC Number | 1.14.15.1 |
| Gene ID | 9617760 |
| Species | Pseudomonas putida |
| Txid | 303 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C14H19NO → C14H19NO2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Ethanol, Water |
| Conditions | 1.5 h, 25°C |
| Transformations | 1. Hydroxylation at an Aliphatic Carbon |
CYP101A1
Substrate Information:
| Substrate Name | (Hexahydro-1(2H)-azocinyl)phenylmethanone |
| Substrate Chemical Formula | C14H19NO |
| Substrate PubChem CID | 3275374 |
| Substrate Smiles | C1CCCN(CCC1)C(=O)C2=CC=CC=C2 |
| Substrate Structure |
Product Information:
| Product Name | (Hexahydro-5-hydroxy-1(2H)-azocinyl)phenylmethanone |
| Product Chemical Formula | C14H19NO2 |
| Product PubChem CID | 165346872 |
| Product CAS Number | 16803-08-0 |
| Product Smiles | C1CC(CCCN(C1)C(=O)C2=CC=CC=C2)O |
| Product Structure |
References:
| Title: | The substrate specificity of cytochrome P450cam. |
| PMID: | 9801821 |
| Journal: | Bioorganic & Medicinal Chemistry (1998) |
| Year: | 1998/3/3 |