Detail Information
P450 Protein:
| P450 Symbol | CYP101A1 |
| Protein Name | Camphor 9-monooxygenase |
| Uniprot ID | P00183 |
| EC Number | 1.14.15.1 |
| Gene ID | 9617760 |
| Species | Pseudomonas putida |
| Txid | 303 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C13H15NO2 → C13H15NO3 + C13H15NO3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Ethanol, Water |
| Conditions | 1.5 h, 25°C |
| Transformations | 1. Hydroxylation at an Aliphatic Carbon |
CYP101A1
+
Substrate Information:
| Substrate Name | Phenyl 7-azabicyclo[2.2.1]heptane-7-carboxylate |
| Substrate Chemical Formula | C13H15NO2 |
| Substrate PubChem CID | 85721476 |
| Substrate Smiles | C1CC2CCC1N2C(=O)OC3=CC=CC=C3 |
| Substrate Structure |
Product Information:
| Product Name | rel-Phenyl (1R,2S,4S)-2-hydroxy-7-azabicyclo[2.2.1]heptane-7-carboxylate |
| Product Chemical Formula | C13H15NO3 |
| Product CAS Number | 1008418-83-4 |
| Product Smiles | O=C(OC=1C=CC=CC1)N2C3CCC2C(O)C3 |
| Product Structure |
| Product Name | rel-Phenyl (1R,2R,4S)-2-hydroxy-7-azabicyclo[2.2.1]heptane-7-carboxylate |
| Product Chemical Formula | C13H15NO3 |
| Product CAS Number | 1008418-02-7 |
| Product Smiles | O=C(OC=1C=CC=CC1)N2C3CCC2C(O)C3 |
| Product Structure |
References:
| Title: | The substrate specificity of cytochrome P450cam. |
| PMID: | 9801821 |
| Journal: | Bioorganic & Medicinal Chemistry (1998) |
| Year: | 1998/3/3 |