Detail Information
P450 Protein:
| P450 Symbol | Cyp2b3 |
| Protein Name | Cytochrome P450 2B3 |
| Uniprot ID | P13107 |
| EC Number | 1.14.14.1 |
| Gene ID | 286953 |
| Species | Rattus norvegicus |
| Txid | 10116 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C7H8 → C7H8O |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Transformations | 1.Hydroxylation of Aromatic Compounds 2.Hydroxylation at an Aromatic Carbon |
Cyp2b3
Substrate Information:
| Substrate Name | Toluene |
| Substrate Chemical Formula | C7H8 |
| Substrate PubChem CID | 1140 |
| Substrate Smiles | CC1=CC=CC=C1 |
| Substrate Structure |
Product Information:
| Product Name | p-Cresol |
| Product Chemical Formula | C7H8O |
| Product PubChem CID | 2879 |
| Product CAS Number | 106-44-5 |
| Product Smiles | CC1=CC=C(C=C1)O |
| Product Structure |
References:
| Title: | Active site dynamics of toluene hydroxylation by cytochrome P-450 |
| DOI: | https://doi.org/10.1021/jo00300a010 |
| Journal: | Journal of Organic Chemistry |
| Year: | 1990/6/1 |