Detail Information
P450 Protein:
| P450 Symbol | CYP101A1 |
| Protein Name | Camphor 5-monooxygenase |
| Uniprot ID | P00183 |
| EC Number | 1.14.15.1 |
| Gene ID | 9617760 |
| Species | Pseudomonas putida |
| Txid | 303 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C8H12O → C8H12O2 + C8H12O2 + C8H12O2 + C8H12O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP101A1
+
+
+
Substrate Information:
| Substrate Name | (1R,4S)-1-Methylbicyclo[2.2.1]heptan-2-one |
| Substrate Chemical Formula | C8H12O |
| Substrate PubChem CID | 11105364 |
| Substrate Smiles | CC12CCC(C1)CC2=O |
| Substrate Structure |
Product Information:
| Product Name | Bicyclo[2.2.1]heptan-2-one, 7-hydroxy-1-methyl-, (1R-anti)- |
| Product Chemical Formula | C8H12O2 |
| Product CAS Number | 119481-19-5 |
| Product Smiles | O=C1CC2CCC1(C)C2O |
| Product Structure |
| Product Name | Bicyclo[2.2.1]heptan-2-one, 3-hydroxy-1-methyl-, (1R-exo)- |
| Product Chemical Formula | C8H12O2 |
| Product CAS Number | 119481-18-4 |
| Product Smiles | O=C1C(O)C2CCC1(C)C2 |
| Product Structure |
| Product Name | Bicyclo[2.2.1]heptan-2-one, 6-hydroxy-1-methyl-, (1S-exo)- |
| Product Chemical Formula | C8H12O2 |
| Product CAS Number | 119481-17-3 |
| Product Smiles | O=C1CC2CC(O)C1(C)C2 |
| Product Structure |
| Product Name | Bicyclo[2.2.1]heptan-2-one, 5-hydroxy-1-methyl-, (1S-exo)- |
| Product Chemical Formula | C8H12O2 |
| Product CAS Number | 119481-16-2 |
| Product Smiles | O=C1CC2CC1(C)CC2O |
| Product Structure |
References:
| Title: | Molecular recognition in cytochrome P-450: alteration of regioselective alkane hydroxylation via protein engineering |
| DOI: | https://doi.org/10.1021/ja00189a057 |
| Journal: | Journal of the American Chemical Society |
| Year: | 1989/3/1 |