Detail Information
P450 Protein:
| P450 Symbol | CYP101A1 |
| Protein Name | Camphor 5-monooxygenase |
| Uniprot ID | P00183 |
| EC Number | 1.14.15.1 |
| Gene ID | 9617760 |
| Species | Pseudomonas putida |
| Txid | 303 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C7H10O → C7H10O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP101A1
Substrate Information:
| Substrate Name | (-)-Norcamphor |
| Substrate Chemical Formula | C7H10O |
| Substrate PubChem CID | 449588 |
| Substrate Smiles | C1CC2CC1CC2=O |
| Substrate Structure |
Product Information:
| Product Name | (1S,4S,5R)-5-Hydroxybicyclo[2.2.1]heptan-2-one |
| Product Chemical Formula | C7H10O2 |
| Product PubChem CID | 13974584 |
| Product CAS Number | 114529-14-5 |
| Product Smiles | C1C2CC(C1CC2=O)O |
| Product Structure |
References:
| Title: | Molecular recognition in cytochrome P-450: alteration of regioselective alkane hydroxylation via protein engineering |
| DOI: | https://doi.org/10.1021/ja00189a057 |
| Journal: | Journal of the American Chemical Society |
| Year: | 1989/3/1 |