Detail Information
P450 Protein:
| P450 Symbol | cyt P450 |
| Protein Name | p450 monoxygenase |
| Uniprot ID | Q4TVP4 |
| Species | Aspergillus ochraceus |
| Txid | 40380 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H12 → C20H12O |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Transformations | 1. Hydroxylation of Aromatic Compounds2. Hydroxylation at an Aromatic Carbon |
cyt P450
Substrate Information:
| Substrate Name | Benzo[a]pyrene |
| Substrate Chemical Formula | C20H12 |
| Substrate PubChem CID | 2336 |
| Substrate Smiles | C1=CC=C2C3=C4C(=CC2=C1)C=CC5=C4C(=CC=C5)C=C3 |
| Substrate Structure |
Product Information:
| Product Name | 2-Hydroxybenzo[a]pyrene |
| Product Chemical Formula | C20H12O |
| Product PubChem CID | 42027 |
| Product CAS Number | 56892-30-9 |
| Product Smiles | C1=CC=C2C3=C4C(=CC2=C1)C=CC5=CC(=CC(=C54)C=C3)O |
| Product Structure |
References:
| Title: | Microsomal benzo(a)pyrene hydroxylase in Aspergillus ochraceus TS: assay and characterization of the enzyme system. |
| PMID: | 6409103 |
| Journal: | Biochemical and Biophysical Research Communications (1983) |
| Year: | 1983/6/15 |