Detail Information

P450 Protein:

P450 SymbolCyb5a
Protein NameCytochrome b5
Uniprot IDP00173
Gene ID 64001
SpeciesRattus norvegicus
Txid 10116
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C9H12S → C9H12OS
Reaction TypeOxidation
Chemical BondS
Transformations1. Oxidation of Thioethers to Sulfoxides and Sulfones

1-(Ethylthio)-4-methylbenzene

Cyb5a

1-[(R)-Ethylsulfinyl]-4-methylbenzene

Substrate Information:

Substrate Name 1-(Ethylthio)-4-methylbenzene
Substrate Chemical FormulaC9H12S
Substrate PubChem CID136431
Substrate SmilesCCSC1=CC=C(C=C1)C
Substrate Structure

Product Information:

Product Name 1-[(R)-Ethylsulfinyl]-4-methylbenzene
Product Chemical FormulaC9H12OS
Product PubChem CID11332695
Product CAS Number1519-40-0
Product SmilesCCS(=O)C1=CC=C(C=C1)C
Product Structure

References:

Title: Chiral sulfoxidations catalyzed by rat liver cytochromes P-450.
PMID: 7093200
Journal: Biochemistry (1982)
Year: 1982/5/11

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics