Detail Information
P450 Protein:
| P450 Symbol | CYP152A2 |
| Protein Name | Cytochrome P450 family protein, YBDT B.subtilis ortholog |
| Uniprot ID | Q97DZ0 |
| EC Number | 1.11.2.4 |
| Species | Clostridium acetobutylicum |
| Txid | 272562 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C8H16O2 → C8H14O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Ethanol;Water |
| Conditions | 24 h, pH 7.4, rt |
| Transformations | 1. Oxidation of Methyl/Methylene to Carbonyl |
CYP152A2
Substrate Information:
| Substrate Name | Octanoic acid |
| Substrate Chemical Formula | C8H16O2 |
| Substrate PubChem CID | 379 |
| Substrate Smiles | O=C(O)CCCCCCC |
| Substrate Structure |
Product Information:
| Product Name | 2-Oxooctanoic acid |
| Product Chemical Formula | C8H14O3 |
| Product PubChem CID | 67600 |
| Product CAS Number | 328-51-8 |
| Product Smiles | O=C(O)C(=O)CCCCCC |
| Product Structure |
References:
| Title: | Biocatalytic Oxidative Cascade for the Conversion of Fatty Acids into α-Ketoacids via Internal H(2) O(2) Recycling. |
| PMID: | 29125663 |
| Journal: | Angewandte Chemie, International Edition |
| Year: | 2018/1/8 |