Detail Information
P450 Protein:
| P450 Symbol | CYP152 |
| Protein Name | |
| Uniprot ID | |
| Species | Sphingomonas paucimobilis |
| Txid | 13689 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C8H16O2 + H2O2 → C8H16O3 + H2O |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
| Solvents | Ethanol, Water |
| Conditions | pH 7.4, rt |
| Transformations | 1. Hydroxylation at an Aliphatic Carbon |
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CYP152
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Substrate Information:
| Substrate Name | Octanoic acid |
| Substrate Chemical Formula | C8H16O2 |
| Substrate PubChem CID | 379 |
| Substrate Smiles | O=C(O)CCCCCCC |
| Substrate Structure |
| Substrate Name | H2O2 |
| Substrate Chemical Formula | H2O2 |
| Substrate PubChem CID | 784 |
| Substrate Smiles | [H]OO[H] |
| Substrate Structure |
Product Information:
| Product Name | (S)-2-Hydroxyoctanoic acid |
| Product Chemical Formula | C8H16O3 |
| Product PubChem CID | 6995013 |
| Product Smiles | CCCCCC[C@H](O)C(=O)O |
| Product Structure |
| Product Name | H2O |
| Product Chemical Formula | H2O |
| Product PubChem CID | 962 |
| Product CAS Number | 7732-18-5 |
| Product Smiles | O |
| Product Structure |
References:
| Title: | Biocatalytic Oxidative Cascade for the Conversion of Fatty Acids into α-Ketoacids via Internal H(2) O(2) Recycling. |
| PMID: | 29125663 |
| Journal: | Angewandte Chemie, International Edition |
| Year: | 2017/12/6 |