Detail Information

P450 Protein:

P450 SymbolCYP101B1
Protein Namecytochrome P450 monooxygenase enzyme CYP101B1
Uniprot ID
SpeciesNovosphingobium aromaticivorans DSM12444
Txid 279238
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C13H12 → C13H12O + C13H12O
Reaction TypeOxidation
Chemical BondCH
SolventsWater
ConditionspH 7.4
Transformations1.Hydroxylation of Aromatic Compounds 2.Hydroxylation at an Aromatic Carbon

1,1′-Biphenyl, 4-methyl- (9CI, ACI)

CYP101B1

[1,1′-Biphenyl]-4-ol, 4′-methyl- (9CI, ACI)

+

[1,1′-Biphenyl]-4-methanol (9CI, ACI)

Substrate Information:

Substrate Name 1,1′-Biphenyl, 4-methyl- (9CI, ACI)
Substrate Chemical FormulaC13H12
Substrate PubChem CID12566
Substrate SmilesC=1C=CC(=CC1)C=2C=CC(=CC2)C
Substrate Structure

Product Information:

Product Name [1,1′-Biphenyl]-4-ol, 4′-methyl- (9CI, ACI)
Product Chemical FormulaC13H12O
Product PubChem CID1382789
Product CAS Number26191-64-0
Product SmilesOC=1C=CC(=CC1)C2=CC=C(C=C2)C
Product Structure
Product Name [1,1′-Biphenyl]-4-methanol (9CI, ACI)
Product Chemical FormulaC13H12O
Product PubChem CID19186
Product CAS Number3597-91-9
Product SmilesOCC=1C=CC(=CC1)C=2C=CC=CC2
Product Structure

References:

Title: The selective oxidation of substituted aromatic hydrocarbons and the observation of uncoupling via redox cycling during naphthalene oxidation by the CYP101B1 system
DOI: https://doi.org/10.1039/C7CY00088J
Journal: Catalysis Science & Technology
Year: 2017/3/10

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics