Detail Information
P450 Protein:
| P450 Symbol | CYP199A2 |
| Protein Name | Cytochrome p450 CYP199A2 |
| Uniprot ID | Q6N8N2 |
| EC Number | 1.14.99.15 |
| Gene ID | 66892909 |
| Species | Rhodopseudomonas palustris |
| Txid | 258594 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C11H8O2 → C11H8O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
| Solvents | Water |
| Conditions | 150 min, pH 7.5, 30°C |
| Transformations | Hydroxylation at an Aromatic Carbon |
CYP199A2
Substrate Information:
| Substrate Name | 2-Naphthoic acid |
| Substrate Chemical Formula | C11H8O2 |
| Substrate PubChem CID | 7123 |
| Substrate Smiles | O=C(O)C=1C=CC=2C=CC=CC2C1 |
| Substrate Structure |
Product Information:
| Product Name | 7-Hydroxy-2-naphthoic acid |
| Product Chemical Formula | C11H8O3 |
| Product PubChem CID | 14512525 |
| Product CAS Number | 613-17-2 |
| Product Smiles | O=C(O)C1=CC=C2C=CC(O)=CC2=C1 |
| Product Structure |
References:
| Title: | Regioselective oxidation of indole- and quinolinecarboxylic acids by cytochrome P450 CYP199A2. |
| PMID: | 20112454 |
| Journal: | Applied Microbiology and Biotechnology |
| Year: | 2009/9/3 |