Detail Information
P450 Protein:
| P450 Symbol | CYP176A1 |
| Protein Name | 1,8-cineole 2-endo-monooxygenase |
| Uniprot ID | Q8VQF6 |
| EC Number | 1.14.14.133 |
| Species | Citrobacter braakii |
| Txid | 57706 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C10H18O → C10H18O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
| Solvents | Water |
| Transformations | Hydroxylation at an Aliphatic Carbon |
CYP176A1
Substrate Information:
| Substrate Name | 1,8-Cineole |
| Substrate Chemical Formula | C10H18O |
| Substrate PubChem CID | 2758 |
| Substrate Smiles | O1C(C)(C)C2CCC1(C)CC2 |
| Substrate Structure |
Product Information:
| Product Name | (1R,4S,6S)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-ol (ACI) |
| Product Chemical Formula | C10H18O2 |
| Product PubChem CID | 6857383 |
| Product CAS Number | 109009-75-8 |
| Product Smiles | OC1CC2CCC1(OC2(C)C)C |
| Product Structure |
References:
| Title: | Cloning, expression and purification of cindoxin, an unusual Fmn-containing cytochrome p450 redox partner. |
| PMID: | 20419722 |
| Journal: | ChemBioChem |
| Year: | 2010/5/10 |